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Meaning of "climacteric" and the crossword clue

- Relating to a climacteric; critical.
- A period in human life in which some great change is supposed to take place in the constitution. The critical periods are thought by some to be the years produced by multiplying 7 into the odd numbers 3, 5, 7, and 9; to which others add the 81st year.
- Any critical period.


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