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Meaning of "smallpox" and the crossword clue

- Acute viral disease, now largely eradicated
- A contagious, constitutional, febrile disease characterized by a peculiar eruption; variola. The cutaneous eruption is at first a collection of papules which become vesicles (first flat, subsequently umbilicated) and then pustules, and finally thick crusts which slough after a certain time, often leaving a pit, or scar.


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